This work is licensed under a Creative Commons Attribution 4.0 International License.
HN-1
General Information
DCTPep ID DCTPep05199
Peptide Name HN-1
Sequence TSPLNIHNGQKL
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
ACP Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating MDA138Tu, MDA159Tu, MDA167Tu, MDA686Tu, MDA1986Tu, and MDA177Tu cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification fluorescein/ FITC/texas red
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C57H96N18O18
Absent amino acids ACDEFMRVWY
Theoretical pI 8.44
Acidic residues 0
Basic residues 2
Polar residues 5
Molecular weight (Average) 1321.5
Molecular weight (Monoisotopic) 1320.71
Common amino acids LN
Net charge 2
Instability index (II) 92.82
Aliphatic index 97.50
Grand average of hydropathicity (GRAVY) -0.750
Half Life
7.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 11118031
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN111225679A
Patent Title Novel Peptide-Based Cancer Imaging Agents
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1505
This work is licensed under a Creative Commons Attribution 4.0 International License.