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DPV15b
General Information
DCTPep ID DCTPep05218
Peptide Name DPV15b
Sequence CGAYDLRRRERQSRLRRRERQSR
Sequence Length 23
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa, PC-3, NCI-H460 and MDA-MB-231
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C119H211N55O35S1
Absent amino acids FHIKMNPTVW
Theoretical pI 11.83
Acidic residues 3
Basic residues 10
Polar residues 5
Molecular weight (Average) 3004.39
Molecular weight (Monoisotopic) 3002.61
Common amino acids R
Net charge 7
Instability index (II) 204.24
Aliphatic index 38.26
Grand average of hydropathicity (GRAVY) -2.343
Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.496, assuming all pairs of Cys residues form cystines
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.496, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US20090186802A1
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1548
This work is licensed under a Creative Commons Attribution 4.0 International License.