This work is licensed under a Creative Commons Attribution 4.0 International License.
YM-3
General Information
DCTPep ID DCTPep05282
Peptide Name YM-3
Sequence GYGRKKRRGRRRTHRLPRRRRRR
Sequence Length 23
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Nanoparticle
Other Modification None
Chiral L
Physicochemical Information
Formula C126H232N66O26
Absent amino acids ACDEFIMNQSVW
Theoretical pI 12.74
Acidic residues 0
Basic residues 16
Polar residues 5
Molecular weight (Average) 3087.65
Molecular weight (Monoisotopic) 3085.89
Common amino acids R
Net charge 16
Instability index (II) 217
Aliphatic index 16.96
Grand average of hydropathicity (GRAVY) -3.065
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.483
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 20100203611A1
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1644
This work is licensed under a Creative Commons Attribution 4.0 International License.