CADY-2c (SEQ ID No: 10)
General Information
DCTPep ID DCTPep05290
Peptide Name CADY-2c (SEQ ID No: 10)
Sequence GLWRALWRALWRSLWKKKRKV
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa or HS-68 cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Cysteamide group
Other Modification None
Chiral L
Physicochemical Information
Formula C132H209N41O23
Absent amino acids CDEFHIMNPQTY
Theoretical pI 12.48
Acidic residues 0
Basic residues 8
Polar residues 2
Molecular weight (Average) 2738.37
Molecular weight (Monoisotopic) 2736.64
Common amino acids KLRW
Net charge 8
Instability index (II) 87.03
Aliphatic index 97.62
Grand average of hydropathicity (GRAVY) -0.733
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 22000
Abs 0.1% (=1 g/l) 8.034
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US7943581B2
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1718