CADY-2c (SEQ ID No: 10)

General Information


DCTPep ID  DCTPep05290

Peptide Name   CADY-2c (SEQ ID No: 10)

Sequence  GLWRALWRALWRSLWKKKRKV

Sequence Length  21

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating HeLa or HS-68 cells



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Acetylation

C-terminal Modification  Cysteamide group

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C132H209N41O23

Absent amino acids  CDEFHIMNPQTY

Theoretical pI  12.48

Acidic residues  0

Basic residues  8

Polar residues  2

Molecular weight (Average)  2738.37

Molecular weight (Monoisotopic)  2736.64

Common amino acids  KLRW

Net charge  8

Instability index (II)  87.03

Aliphatic index  97.62

Grand average of hydropathicity (GRAVY)  -0.733

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 22000
  Abs 0.1% (=1 g/l) 8.034

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US7943581B2

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  1718

DCTPep is developed by Dr.Zheng's team.