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AlkCWK18 (SEQ ID NO:3)
General Information
DCTPep ID DCTPep05309
Peptide Name AlkCWK18 (SEQ ID NO:3)
Sequence CWKKKKKKKKKKKKKKKKKK
Sequence Length 20
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HepG2 and COS-7 cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C122H233N39O21S1
Absent amino acids ADEFGHILMNPQRSTVY
Theoretical pI 10.91
Acidic residues 0
Basic residues 18
Polar residues 1
Molecular weight (Average) 2614.5
Molecular weight (Monoisotopic) 2612.81
Common amino acids K
Net charge 18
Instability index (II) 21.34
Aliphatic index 0.00
Grand average of hydropathicity (GRAVY) -3.430
Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 2.104, assuming all pairs of Cys residues form cystines
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 2.104, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US7112442B2
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1784
This work is licensed under a Creative Commons Attribution 4.0 International License.