AlkCWK18 (SEQ ID NO:3)

General Information


DCTPep ID  DCTPep05309

Peptide Name   AlkCWK18 (SEQ ID NO:3)

Sequence  CWKKKKKKKKKKKKKKKKKK

Sequence Length  20

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating HepG2 and COS-7 cells



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Acetylation

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C122H233N39O21S1

Absent amino acids  ADEFGHILMNPQRSTVY

Theoretical pI  10.91

Acidic residues  0

Basic residues  18

Polar residues  1

Molecular weight (Average)  2614.5

Molecular weight (Monoisotopic)  2612.81

Common amino acids  K

Net charge  18

Instability index (II)  21.34

Aliphatic index  0.00

Grand average of hydropathicity (GRAVY)  -3.430

Half Life 
  1.2 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 5500
  Abs 0.1% (=1 g/l) 2.104, assuming all pairs of Cys residues form cystines
  Ext. coefficient 5500
  Abs 0.1% (=1 g/l) 2.104, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US7112442B2

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  1784

DCTPep is developed by Dr.Zheng's team.