This work is licensed under a Creative Commons Attribution 4.0 International License.
MCoK6A mutant
General Information
DCTPep ID DCTPep05312
Peptide Name MCoK6A mutant
Sequence GGVCPAILKKCRRDSDCPGACICRGNGYCGSGSD
Sequence Length 34
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating RAW 264.7 and MCF-7
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Not available
N-terminal Modification Alexa-488
C-terminal Modification Cyclization
Other Modification None
Chiral L
Physicochemical Information
Formula C135H224N46O46S6
Absent amino acids EFHMQTW
Theoretical pI 8.33
Acidic residues 3
Basic residues 5
Polar residues 18
Molecular weight (Average) 3419.9
Molecular weight (Monoisotopic) 3417.49
Common amino acids G
Net charge 2
Instability index (II) 54.52
Aliphatic index 48.82
Grand average of hydropathicity (GRAVY) -0.276
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1865
Abs 0.1% (=1 g/l) 0.545, assuming all pairs of Cys residues form cystines
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.436, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21873420
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1797
This work is licensed under a Creative Commons Attribution 4.0 International License.