Peptide Libraray

kT20K mutant

General Information

DCTPep ID DCTPep05315

Peptide Name kT20K mutant

Sequence GLPVCGETCVGGTCNTPGCKCSWPVCTRN

Sequence Length 29

UniProt ID Not available

PubChem CID Not available

Origin Protein derived

Type Native peptide

Classification

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Penetrating RAW 264.7 and MCF-7

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Cyclic

Disulfide/Other Bond Not available

N-terminal Modification Alexa-488

C-terminal Modification Cyclization

Other Modification None

Chiral L

Physicochemical Information

Formula C119H192N36O39S6

Absent amino acids ADFHIMQY

Theoretical pI 7.78

Acidic residues 1

Basic residues 2

Polar residues 18

Molecular weight (Average) 2943.41

Molecular weight (Monoisotopic) 2941.25

Common amino acids C

Net charge 1

Instability index (II) 35.35

Aliphatic index 43.45

Grand average of hydropathicity (GRAVY) 0.041

Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 5875
Abs 0.1% (=1 g/l) 1.996, assuming all pairs of Cys residues form cystines
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 1.869, assuming all Cys residues are reduced

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 21873420

Title Not available

Doi Not available

Year Not available

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available

External Code

Cppsite ID 1800