This work is licensed under a Creative Commons Attribution 4.0 International License.
KLA-TAT(47-57)
General Information
DCTPep ID DCTPep05356
Peptide Name KLA-TAT(47-57)
Sequence KLAKLAKKLAKLAKGRKKRRQRRRP
Sequence Length 25
UniProt ID Not available
PubChem CID Not available
Origin Chimeric
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating Beas-2B, A549, Caco-2 and AGS
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C132H252N52O27
Absent amino acids CDEFHIMNSTVWY
Theoretical pI 12.71
Acidic residues 0
Basic residues 14
Polar residues 1
Molecular weight (Average) 2999.79
Molecular weight (Monoisotopic) 2997.99
Common amino acids K
Net charge 14
Instability index (II) 89.8
Aliphatic index 78.40
Grand average of hydropathicity (GRAVY) -1.652
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23469189
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2034
This work is licensed under a Creative Commons Attribution 4.0 International License.