Peptide Libraray

p28

General Information

DCTPep ID DCTPep05372

Peptide Name p28

Sequence LSTAADMQGVVTDGMASGLDKDYLKPDD

Sequence Length 28

UniProt ID Not available

PubChem CID Not available

Origin Protein derived

Type Native peptide

Classification

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Penetrating MCF-7, MDA-MB-231, and T47D, HCT116 and HT29, HT1080, (HTB-88), osteosarcoma (TE85), rhabdomyosarcoma (RD), glioblastoma (U87 and LN229), neuroblastoma (SK-N-BE2), prostate cancer (DU145), pancreatic cancer (MIA-Paca2) and ovarian cancer (ES-2)]. Melanoma lines (UISO-Mel-23, 29

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C122H197N31O47S2

Absent amino acids CEFHINRW

Theoretical pI 3.85

Acidic residues 6

Basic residues 2

Polar residues 8

Molecular weight (Average) 2914.21

Molecular weight (Monoisotopic) 2912.34

Common amino acids D

Net charge -4

Instability index (II) -6.16

Aliphatic index 73.21

Grand average of hydropathicity (GRAVY) -0.371

Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.511

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 23952735

Title Not available

Doi Not available

Year Not available

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available

External Code

Cppsite ID 2103