hLF Q6A

General Information


DCTPep ID  DCTPep05412

Peptide Name   hLF Q6A

Sequence  KCFQWARNMRKVRGPPVSCIKR

Sequence Length  22

UniProt ID  Not available

PubChem CID  Not available

Origin  Protein derived

Type  Native peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating HeLa, Jurkat E6.1 leukemia cells, Ovcar-3 cells, and Caco-2 cells



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Fluorescein

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C116H194N40O26S3

Absent amino acids  DEHLTY

Theoretical pI  11.57

Acidic residues  0

Basic residues  7

Polar residues  5

Molecular weight (Average)  2661.25

Molecular weight (Monoisotopic)  2659.42

Common amino acids  R

Net charge  7

Instability index (II)  40.46

Aliphatic index  48.64

Grand average of hydropathicity (GRAVY)  -0.800

Half Life 
  1.3 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  3 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 5625
  Abs 0.1% (=1 g/l) 2.114, assuming all pairs of Cys residues form cystines
  Ext. coefficient 5500
  Abs 0.1% (=1 g/l) 2.067, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24270856

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2180

DCTPep is developed by Dr.Zheng's team.