Pep3(Mutant)

General Information


DCTPep ID  DCTPep05428

Peptide Name   Pep3(Mutant)

Sequence  GRGDGPRRKKKKGPRRKKKKGPRR

Sequence Length  24

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating HeLa and A549



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Acetylation

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C119H223N53O27

Absent amino acids  ACEFHILMNQSTVWY

Theoretical pI  12.41

Acidic residues  1

Basic residues  15

Polar residues  5

Molecular weight (Average)  2828.42

Molecular weight (Monoisotopic)  2826.77

Common amino acids  K

Net charge  14

Instability index (II)  61.15

Aliphatic index  0.00

Grand average of hydropathicity (GRAVY)  -3.042

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24462902

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2196

DCTPep is developed by Dr.Zheng's team.