This work is licensed under a Creative Commons Attribution 4.0 International License.
Mgpe-4
General Information
DCTPep ID DCTPep05440
Peptide Name Mgpe-4
Sequence LLYWFRRRHRHHRRRHRR
Sequence Length 18
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating A549, MCF-7, HeLa, HEK, T47D, B16, MDA-MB 231, B35 and U 87, CHO-K1, H-1299, JURKAT and RAW
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C119H188N54O20
Absent amino acids ACDEGIKMNPQSTV
Theoretical pI 12.54
Acidic residues 0
Basic residues 13
Polar residues 1
Molecular weight (Average) 2695.15
Molecular weight (Monoisotopic) 2693.54
Common amino acids R
Net charge 13
Instability index (II) 194.89
Aliphatic index 43.33
Grand average of hydropathicity (GRAVY) -2.506
Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 2.594
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24816284
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2238
This work is licensed under a Creative Commons Attribution 4.0 International License.