Mgpe-4

General Information


DCTPep ID  DCTPep05440

Peptide Name   Mgpe-4

Sequence  LLYWFRRRHRHHRRRHRR

Sequence Length  18

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating A549, MCF-7, HeLa, HEK, T47D, B16, MDA-MB 231, B35 and U 87, CHO-K1, H-1299, JURKAT and RAW



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C119H188N54O20

Absent amino acids  ACDEGIKMNPQSTV

Theoretical pI  12.54

Acidic residues  0

Basic residues  13

Polar residues  1

Molecular weight (Average)  2695.15

Molecular weight (Monoisotopic)  2693.54

Common amino acids  R

Net charge  13

Instability index (II)  194.89

Aliphatic index  43.33

Grand average of hydropathicity (GRAVY)  -2.506

Half Life 
  5.5 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 6990
  Abs 0.1% (=1 g/l) 2.594

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24816284

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2238

DCTPep is developed by Dr.Zheng's team.