R7-SRC1(1222-1245)

General Information


DCTPep ID  DCTPep05464

Peptide Name   R7-SRC1(1222-1245)

Sequence  PKKKRKVRRRRRRRPQMQQNVFQYPGAGMVPQGEANF

Sequence Length  37

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating MCF-7, MDA-MB-231, and HeLa



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

SequenceNo structure available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  NLS

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C194H324N72O48S2

Absent amino acids  CDHILSTW

Theoretical pI  12.23

Acidic residues  1

Basic residues  12

Polar residues  6

Molecular weight (Average)  4497.28

Molecular weight (Monoisotopic)  4494.46

Common amino acids  R

Net charge  11

Instability index (II)  126.02

Aliphatic index  28.92

Grand average of hydropathicity (GRAVY)  -1.700

Half Life 
  >20 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  ? (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 0.331

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24705462

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2267

DCTPep is developed by Dr.Zheng's team.