This work is licensed under a Creative Commons Attribution 4.0 International License.
G(SG)4Pen
General Information
DCTPep ID DCTPep05490
Peptide Name G(SG)4Pen
Sequence GSGSGSGSGRQIKIWFQNRRMKWKKGC
Sequence Length 27
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa, KG1a cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C131H211N45O35S2
Absent amino acids ADEHLPTVY
Theoretical pI 11.75
Acidic residues 0
Basic residues 7
Polar residues 12
Molecular weight (Average) 3040.52
Molecular weight (Monoisotopic) 3038.56
Common amino acids G
Net charge 7
Instability index (II) 28.54
Aliphatic index 28.89
Grand average of hydropathicity (GRAVY) -1.141
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 3.618, assuming all pairs of Cys residues form cystines
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 3.618, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25108152
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2295
This work is licensed under a Creative Commons Attribution 4.0 International License.