Peptide Libraray

FITC-WT1-pTj

General Information

DCTPep ID DCTPep05494

Peptide Name FITC-WT1-pTj

Sequence KDCERRFSRSDQLKRHQRRHTGVKPFQK

Sequence Length 28

UniProt ID Not available

PubChem CID Not available

Origin Protein derived

Type Native peptide

Classification

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Penetrating A2058 human melanoma cells, B16F10-Nex2 syngeneic murine melanoma, HFF and MEF cells-- A2058 and SK-MEL-28, MCF-7 and MDA-MB231, OVCAR-3 and HL-62

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C149H247N57O41S1

Absent amino acids AIMNWY

Theoretical pI 11.38

Acidic residues 3

Basic residues 12

Polar residues 5

Molecular weight (Average) 3525.02

Molecular weight (Monoisotopic) 3522.87

Common amino acids R

Net charge 9

Instability index (II) 92.93

Aliphatic index 24.29

Grand average of hydropathicity (GRAVY) -2.079

Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 24490140

Title Not available

Doi Not available

Year Not available

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available

External Code

Cppsite ID 2304