Peptide Libraray

sgRNA-CPP

General Information

DCTPep ID DCTPep05496

Peptide Name sgRNA-CPP

Sequence CGGGRRRRRRRRRLLLL

Sequence Length 17

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Penetrating HEK293T cells, HeLa cell, NCCIT cell line, human dermal fibroblast cells and The H9 human embryonic stem

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C87H168N44O18S1

Absent amino acids ADEFHIKMNPQSTVWY

Theoretical pI 12.54

Acidic residues 0

Basic residues 9

Polar residues 4

Molecular weight (Average) 2150.63

Molecular weight (Monoisotopic) 2149.33

Common amino acids R

Net charge 9

Instability index (II) 293.48

Aliphatic index 91.76

Grand average of hydropathicity (GRAVY) -1.412

Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 24696462

Title Not available

Doi Not available

Year Not available

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available

External Code

Cppsite ID 2309