Tat

General Information


DCTPep ID  DCTPep05498

Peptide Name   Tat

Sequence  RKKRRQRRRGGG

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Protein derived

Type  Native peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating HT29 and K562



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C59H115N33O14

Absent amino acids  ACDEFHILMNPSTVWY

Theoretical pI  12.70

Acidic residues  0

Basic residues  8

Polar residues  3

Molecular weight (Average)  1510.77

Molecular weight (Monoisotopic)  1509.93

Common amino acids  R

Net charge  8

Instability index (II)  209.08

Aliphatic index  0.00

Grand average of hydropathicity (GRAVY)  -3.292

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  2 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24218116

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2321

DCTPep is developed by Dr.Zheng's team.