D3

General Information


DCTPep ID  DCTPep05573

Peptide Name   D3

Sequence  RLRLRLRLRLRLRLRLKNNKNNKNNKNNKKKKKKKGYK

Sequence Length  38

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating HeLa, CHO and Jurkat cells



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C211H390N82O48

Absent amino acids  ACDEFHIMPQSTVW

Theoretical pI  12.49

Acidic residues  0

Basic residues  20

Polar residues  10

Molecular weight (Average)  4843.94

Molecular weight (Monoisotopic)  4841.06

Common amino acids  K

Net charge  20

Instability index (II)  63.44

Aliphatic index  82.11

Grand average of hydropathicity (GRAVY)  -2.161

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  2 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 0.308

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24870379

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2416

DCTPep is developed by Dr.Zheng's team.