D4

General Information


DCTPep ID  DCTPep05574

Peptide Name   D4

Sequence  GYGYGYGYGYGYGYGYKKRKKRKKRKKRKQQKQQKRRK

Sequence Length  38

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating HeLa, CHO and Jurkat cells



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C216H346N72O51

Absent amino acids  ACDEFHILMNPSTVW

Theoretical pI  10.71

Acidic residues  0

Basic residues  18

Polar residues  16

Molecular weight (Average)  4767.58

Molecular weight (Monoisotopic)  4764.67

Common amino acids  K

Net charge  18

Instability index (II)  56.79

Aliphatic index  0.00

Grand average of hydropathicity (GRAVY)  -2.668

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 11920
  Abs 0.1% (=1 g/l) 2.500

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24870379

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2417

DCTPep is developed by Dr.Zheng's team.