This work is licensed under a Creative Commons Attribution 4.0 International License.
D4
General Information
DCTPep ID DCTPep05574
Peptide Name D4
Sequence GYGYGYGYGYGYGYGYKKRKKRKKRKKRKQQKQQKRRK
Sequence Length 38
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa, CHO and Jurkat cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C216H346N72O51
Absent amino acids ACDEFHILMNPSTVW
Theoretical pI 10.71
Acidic residues 0
Basic residues 18
Polar residues 16
Molecular weight (Average) 4767.58
Molecular weight (Monoisotopic) 4764.67
Common amino acids K
Net charge 18
Instability index (II) 56.79
Aliphatic index 0.00
Grand average of hydropathicity (GRAVY) -2.668
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11920
Abs 0.1% (=1 g/l) 2.500
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24870379
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2417
This work is licensed under a Creative Commons Attribution 4.0 International License.