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LK-2
General Information
DCTPep ID DCTPep05587
Peptide Name LK-2
Sequence LKKLCKLLKKLCKLAG
Sequence Length 16
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C83H158N22O17S2
Absent amino acids DEFHIMNPQRSTVWY
Theoretical pI 10.05
Acidic residues 0
Basic residues 6
Polar residues 3
Molecular weight (Average) 1800.42
Molecular weight (Monoisotopic) 1799.16
Common amino acids KL
Net charge 6
Instability index (II) -22.46
Aliphatic index 152.50
Grand average of hydropathicity (GRAVY) 0.362
Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.069, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25056130
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2434
This work is licensed under a Creative Commons Attribution 4.0 International License.