This work is licensed under a Creative Commons Attribution 4.0 International License.
VG-21
General Information
DCTPep ID DCTPep05588
Peptide Name VG-21
Sequence VTPHHVLVDEYTGEWVDSQFK
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HEp-2, HeLa, Vero and Cos-7 cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C114H164N28O35
Absent amino acids ACIMNR
Theoretical pI 4.72
Acidic residues 4
Basic residues 3
Polar residues 5
Molecular weight (Average) 2486.72
Molecular weight (Monoisotopic) 2485.19
Common amino acids V
Net charge -1
Instability index (II) -24.11
Aliphatic index 73.81
Grand average of hydropathicity (GRAVY) -0.514
Half Life
100 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 2.811
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25154664
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2436
This work is licensed under a Creative Commons Attribution 4.0 International License.