T7-LP

General Information


DCTPep ID  DCTPep05622

Peptide Name   T7-LP

Sequence  CHAIYPRH

Sequence Length  8

UniProt ID  Not available

PubChem CID  146681219 

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating A549



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Rhodamine LP

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C44H65N15O10S1

Absent amino acids  DEFGKLMNQSTVW

Theoretical pI  8.24

Acidic residues  0

Basic residues  3

Polar residues  2

Molecular weight (Average)  996.15

Molecular weight (Monoisotopic)  995.48

Common amino acids  H

Net charge  3

Instability index (II)  79.57

Aliphatic index  61.25

Grand average of hydropathicity (GRAVY)  -0.625

Half Life 
  1.2 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 1.496, assuming all pairs of Cys residues form cystines
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 1.496, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 25482610

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2519

DCTPep is developed by Dr.Zheng's team.