This work is licensed under a Creative Commons Attribution 4.0 International License.
TP
General Information
DCTPep ID DCTPep05623
Peptide Name TP
Sequence GWTLNSAGYLLGKINLKALAALAKKIL
Sequence Length 27
UniProt ID Not available
PubChem CID Not available
Origin Chimeric
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HT29 and HCT116
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification FITC labelled streptavidin
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C134H226N34O33
Absent amino acids CDEFHMPQRV
Theoretical pI 10.18
Acidic residues 0
Basic residues 4
Polar residues 8
Molecular weight (Average) 2841.48
Molecular weight (Monoisotopic) 2839.71
Common amino acids L
Net charge 4
Instability index (II) 0.04
Aliphatic index 148.52
Grand average of hydropathicity (GRAVY) 0.633
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 2.460
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25511292
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2520
This work is licensed under a Creative Commons Attribution 4.0 International License.