TP-biot1

General Information


DCTPep ID  DCTPep05624

Peptide Name   TP-biot1

Sequence  GWTLNSAGYLLGKINLKALAALAKKIL

Sequence Length  27

UniProt ID  Not available

PubChem CID  Not available

Origin  Chimeric

Type  Native peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating HT29 and HCT116



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Biotinylation

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C134H226N34O33

Absent amino acids  CDEFHMPQRV

Theoretical pI  10.18

Acidic residues  0

Basic residues  4

Polar residues  8

Molecular weight (Average)  2841.48

Molecular weight (Monoisotopic)  2839.71

Common amino acids  L

Net charge  4

Instability index (II)  0.04

Aliphatic index  148.52

Grand average of hydropathicity (GRAVY)  0.633

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 6990
  Abs 0.1% (=1 g/l) 2.460

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 25511292

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2521

DCTPep is developed by Dr.Zheng's team.