This work is licensed under a Creative Commons Attribution 4.0 International License.
MTpl-3
General Information
DCTPep ID DCTPep05628
Peptide Name MTpl-3
Sequence KWCFAVCYAGICYAACAGK
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating Plant cells, HeLa cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Biotinylation
C-terminal Modification
Other Modification None
Chiral L
Physicochemical Information
Formula C92H134N22O22S4
Absent amino acids DEHLMNPQRST
Theoretical pI 8.50
Acidic residues 0
Basic residues 2
Polar residues 8
Molecular weight (Average) 2028.45
Molecular weight (Monoisotopic) 2026.89
Common amino acids A
Net charge 2
Instability index (II) 48.59
Aliphatic index 62.11
Grand average of hydropathicity (GRAVY) 0.968
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 8730
Abs 0.1% (=1 g/l) 4.304, assuming all pairs of Cys residues form cystines
Ext. coefficient 8480
Abs 0.1% (=1 g/l) 4.181, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25514997
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2528
This work is licensed under a Creative Commons Attribution 4.0 International License.