This work is licensed under a Creative Commons Attribution 4.0 International License.
TAT-cysteine peptide
General Information
DCTPep ID DCTPep05642
Peptide Name TAT-cysteine peptide
Sequence AYGRKKRRQRRR
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HepG2, HeLa cell
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C67H123N33O15
Absent amino acids CDEFHILMNPSTVW
Theoretical pI 12.31
Acidic residues 0
Basic residues 8
Polar residues 2
Molecular weight (Average) 1630.93
Molecular weight (Monoisotopic) 1629.99
Common amino acids R
Net charge 8
Instability index (II) 188.51
Aliphatic index 8.33
Grand average of hydropathicity (GRAVY) -3.183
Half Life
4.4 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.914
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24709209
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2590
This work is licensed under a Creative Commons Attribution 4.0 International License.