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CPPL
General Information
DCTPep ID DCTPep05651
Peptide Name CPPL
Sequence MAPQRDTVGGRTTPPSWGPAKAQLRNSCA
Sequence Length 29
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HEK and HeLa cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C128H209N43O40S2
Absent amino acids EFHIY
Theoretical pI 10.76
Acidic residues 1
Basic residues 4
Polar residues 10
Molecular weight (Average) 3054.45
Molecular weight (Monoisotopic) 3052.51
Common amino acids AP
Net charge 3
Instability index (II) 61.82
Aliphatic index 37.24
Grand average of hydropathicity (GRAVY) -0.828
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 1.801, assuming all pairs of Cys residues form cystines
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 1.801, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22076844
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2620
This work is licensed under a Creative Commons Attribution 4.0 International License.