2

General Information


DCTPep ID  DCTPep05676

Peptide Name   2

Sequence  DSLKSYWYLQKFSWR

Sequence Length  15

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating Many Human neoplastic cells including HeLa, Lovo, A549, MCF-7,MKN45,HepG2, LNCap, KPK,U2OS, RC-15,RD-ES,H28,K562,U251,NHDF



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C97H135N23O24

Absent amino acids  ACEGHIMNPTV

Theoretical pI  9.53

Acidic residues  1

Basic residues  3

Polar residues  5

Molecular weight (Average)  2007.28

Molecular weight (Monoisotopic)  2006.01

Common amino acids  S

Net charge  2

Instability index (II)  31.33

Aliphatic index  52.00

Grand average of hydropathicity (GRAVY)  -1.047

Half Life 
  1.1 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 13980
  Abs 0.1% (=1 g/l) 6.965

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 22805558

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2729

DCTPep is developed by Dr.Zheng's team.