This work is licensed under a Creative Commons Attribution 4.0 International License.
7
General Information
DCTPep ID DCTPep05677
Peptide Name 7
Sequence KLWMRWWSPTTRRYG
Sequence Length 15
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating Many Human neoplastic cells including HeLa, Lovo, A549, MCF-7,MKN45,HepG2, LNCap, KPK,U2OS, RC-15,RD-ES,H28,K562,U251,NHDF
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C95H138N28O20S1
Absent amino acids ACDEFHINQV
Theoretical pI 11.72
Acidic residues 0
Basic residues 4
Polar residues 5
Molecular weight (Average) 2024.38
Molecular weight (Monoisotopic) 2023.04
Common amino acids RW
Net charge 4
Instability index (II) 125.2
Aliphatic index 26.00
Grand average of hydropathicity (GRAVY) -1.327
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 17990
Abs 0.1% (=1 g/l) 8.887
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22805558
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2730
This work is licensed under a Creative Commons Attribution 4.0 International License.