Peptide Libraray

General Information

DCTPep ID DCTPep05682

Peptide Name 44

Sequence KRPTMRFRYTWNPMK

Sequence Length 15

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

ACP Cancer targeted peptides Stapled Peptides

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Chymotrypsin hydrolysis

Affinity Not available

Mechanism Penetrating Many Human neoplastic cells including HeLa, Lovo, A549, MCF-7,MKN45,HepG2, LNCap, KPK,U2OS, RC-15,RD-ES,H28,K562,U251,NHDF

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C91H142N28O20S2

Absent amino acids ACDEGHILQSV

Theoretical pI 11.73

Acidic residues 0

Basic residues 5

Polar residues 4

Molecular weight (Average) 2012.42

Molecular weight (Monoisotopic) 2011.04

Common amino acids R

Net charge 5

Instability index (II) 19.45

Aliphatic index 0.00

Grand average of hydropathicity (GRAVY) -1.667

Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 3.473

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 22805558

Title Not available

Doi Not available

Year Not available

Patent

Patent ID CN113797335A

Patent Title Self-assembled photosensitive nanofiber material based on polypeptide, preparation method of self-assembled photosensitive nanofiber material and application of self-assembled photosensitive nanofiber material in preparation of antitumor drugs

Other Iinformation Not available

Other Published ID Not available

External Code

Cppsite ID 2735