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Tat
General Information
DCTPep ID DCTPep05712
Peptide Name Tat
Sequence CALNNYGRKKRRQRRR
Sequence Length 16
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating RAW 264.7 and HepG2 cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C84H151N39O21S1
Absent amino acids DEFHIMPSTVW
Theoretical pI 12.01
Acidic residues 0
Basic residues 8
Polar residues 5
Molecular weight (Average) 2075.43
Molecular weight (Monoisotopic) 2074.17
Common amino acids R
Net charge 8
Instability index (II) 143.88
Aliphatic index 30.63
Grand average of hydropathicity (GRAVY) -2.431
Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.718, assuming all pairs of Cys residues form cystines
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.718, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23184894
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2773
This work is licensed under a Creative Commons Attribution 4.0 International License.