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PL
General Information
DCTPep ID DCTPep05714
Peptide Name PL
Sequence RLLRLLRRLLRLLRRLLRC
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating A549 and NCI-H322 cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C111H213N43O20S1
Absent amino acids ADEFGHIKMNPQSTVWY
Theoretical pI 12.48
Acidic residues 0
Basic residues 8
Polar residues 1
Molecular weight (Average) 2502.25
Molecular weight (Monoisotopic) 2500.67
Common amino acids L
Net charge 8
Instability index (II) 120.45
Aliphatic index 205.26
Grand average of hydropathicity (GRAVY) 0.237
Half Life
1 hours (mammalian reticulocytes, in vitro).
2 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23384441
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2777
This work is licensed under a Creative Commons Attribution 4.0 International License.