PE1

General Information


DCTPep ID  DCTPep05717

Peptide Name   PE1

Sequence  RGERGERRELRLERGELRC

Sequence Length  19

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating A549 and NCI-H322 cells



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C94H168N40O30S1

Absent amino acids  ADFHIKMNPQSTVWY

Theoretical pI  10.07

Acidic residues  5

Basic residues  7

Polar residues  4

Molecular weight (Average)  2370.68

Molecular weight (Monoisotopic)  2369.26

Common amino acids  R

Net charge  2

Instability index (II)  34.58

Aliphatic index  61.58

Grand average of hydropathicity (GRAVY)  -1.911

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  2 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all pairs of Cys residues form cystines
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 23384441

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2780

DCTPep is developed by Dr.Zheng's team.