This work is licensed under a Creative Commons Attribution 4.0 International License.
i7-01s-06
General Information
DCTPep ID DCTPep05806
Peptide Name i7-01s-06
Sequence RLISⓍLLDREKⓍRGV
Sequence Length 15
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
ACP Cancer targeted peptides Stapled Peptides Induce necrosis
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity HEK 293T: Negligible cytotoxicity
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic (Stapled)
Disulfide/Other Bond Stapled: Ⓧ(5) and Ⓧ (12) are cross-linked by hydrocarbon stapling
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification Ⓧ(5)=(R)-2-Amino-2-methyl-9-decenoic acid; Ⓧ(12)=(S)-2-Amino-2-methyl-6-heptenoic acid
Chiral L
Physicochemical Information
Formula Not Applicable
Absent amino acids Not Applicable
Theoretical pI Not Applicable
Acidic residues Not Applicable
Basic residues Not Applicable
Polar residues Not Applicable
Molecular weight (Average) Not Applicable
Molecular weight (Monoisotopic) Not Applicable
Common amino acids Not Applicable
Net charge Not Applicable
Instability index (II) Not Applicable
Aliphatic index Not Applicable
Grand average of hydropathicity (GRAVY) Not Applicable
Half Life
Not Applicable
Extinction coefficients
Not Applicable
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID WO2022237853A1
Patent Title Beclin1-Targeted Stapled Peptide and Pharmaceutical Composition
Other Iinformation Not available
Other Published ID CN113402588A CN113402588B
This work is licensed under a Creative Commons Attribution 4.0 International License.