i7-01s-15

General Information


DCTPep ID  DCTPep05815

Peptide Name   i7-01s-15

Sequence  RLISⓍREDREKⓍRAV

Sequence Length  15

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

ACP Cancer targeted peptides Stapled Peptides Induce necrosis



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  HEK 293T: Negligible cytotoxicity

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic (Stapled)

Disulfide/Other Bond  Stapled: Ⓧ(5) and Ⓧ (12) are cross-linked by hydrocarbon stapling

N-terminal Modification  Acetylation

C-terminal Modification  Amidation

Other Modification  Ⓧ(5)=(R)-2-Amino-2-methyl-9-decenoic acid; Ⓧ(12)=(S)-2-Amino-2-methyl-6-heptenoic acid

Chiral  L



Physicochemical Information


Formula  Not Applicable

Absent amino acids  Not Applicable

Theoretical pI  Not Applicable

Acidic residues  Not Applicable

Basic residues  Not Applicable

Polar residues  Not Applicable

Molecular weight (Average)  Not Applicable

Molecular weight (Monoisotopic)  Not Applicable

Common amino acids  Not Applicable

Net charge  Not Applicable

Instability index (II)  Not Applicable

Aliphatic index  Not Applicable

Grand average of hydropathicity (GRAVY)  Not Applicable

Half Life 
  Not Applicable

Extinction coefficients 
  Not Applicable

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID WO2022237853A1

Patent Title  Beclin1-Targeted Stapled Peptide and Pharmaceutical Composition

Other Iinformation  Not available

Other Published ID  CN113402588A  CN113402588B 




DCTPep is developed by Dr.Zheng's team.