Peptide Libraray

SEQ ID NO.1 of Patent CN114409737A

General Information

DCTPep ID DCTPep06003

Peptide Name SEQ ID NO.1 of Patent CN114409737A

Sequence KLLKFIWRI

Sequence Length 9

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

ACP Tumor active peptide

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
HeLa	Human papillomavirus-related endocervical adenocarcinoma	45±5.3% Survival=100 μΜ	MTT assay	24 h	Patent

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Human epithelial cells: 97±7.1% Survival=100 μM

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C62H101N15O10

Absent amino acids ACDEGHMNPQSTVY

Theoretical pI 11.17

Acidic residues 0

Basic residues 3

Polar residues 0

Molecular weight (Average) 1216.58

Molecular weight (Monoisotopic) 1215.79

Common amino acids IKL

Net charge 3

Instability index (II) -9.98

Aliphatic index 173.33

Grand average of hydropathicity (GRAVY) 0.689

Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 4.521

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID CN114409737A

Patent Title Novel anti-tumor peptide and application thereof

Other Iinformation Not available

Other Published ID Not available