Peptide Libraray

Ped4

General Information

DCTPep ID DCTPep06004

Peptide Name Ped4

Sequence FLWSRILFRLRK

Sequence Length 12

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

ACP Tumor active peptide

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
U87	Glioblastoma	IC50=15.85±0.38 μM	CCK-8 assay	24 h	Patent
T98G	Glioblastoma	IC50=23.37±2.03 μM	CCK-8 assay	24 h	Patent
U251	Astrocytoma	IC50=25.68±0.74 μM	CCK-8 assay	24 h	Patent

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C80H127N23O14

Absent amino acids ACDEGHMNPQTVY

Theoretical pI 12.30

Acidic residues 0

Basic residues 4

Polar residues 1

Molecular weight (Average) 1635.03

Molecular weight (Monoisotopic) 1633.99

Common amino acids LR

Net charge 4

Instability index (II) 77.05

Aliphatic index 130.00

Grand average of hydropathicity (GRAVY) 0.200

Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 3.364

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID CN114989259A

Patent Title Small molecule peptide Ped4 and application

Other Iinformation Not available

Other Published ID Not available