Peptide Libraray

PEP01

General Information

DCTPep ID DCTPep06007

Peptide Name PEP01

Sequence ELQSTGRKVA

Sequence Length 10

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

ACP Tumor active peptide

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
SK-MEL-103	Melanoma	48% Survival=10 μg/ml	CCK-8 assay	72h	Patent
HeLa S3	Breast cancer	48% Survival=25 μg/ml	CCK-8 assay	72h	Patent
A549	Lung adenocarcinoma	62% Survival=10 μg/ml	CCK-8 assay	24h	Patent

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C45H81N15O16

Absent amino acids CDFHIMNPWY

Theoretical pI 8.85

Acidic residues 1

Basic residues 2

Polar residues 3

Molecular weight (Average) 1088.23

Molecular weight (Monoisotopic) 1087.6

Common amino acids AEGKLQRSTV

Net charge 1

Instability index (II) 68.56

Aliphatic index 78.00

Grand average of hydropathicity (GRAVY) -0.750

Half Life
1 hours (mammalian reticulocytes, in vitro).
30 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).

Extinction coefficients
Should not be visible by UV spectrophotometry.

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID CN113354711A

Patent Title Anti-cancer bioactive peptide and synthesis method thereof

Other Iinformation Not available

Other Published ID Not available