Peptide Libraray

Bax-BH3

General Information

DCTPep ID DCTPep06008

Peptide Name Bax-BH3

Sequence DASTKKLSECLRRIGDELDS

Sequence Length 20

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

ACP Tumor active peptide Pro-apoptosis

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
A549	Lung adenocarcinoma	38% Survival=100 μg/ml	MTT assay	24h	Patent

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C91H158N28O35S1

Absent amino acids FHMNPQVWY

Theoretical pI 4.86

Acidic residues 5

Basic residues 4

Polar residues 6

Molecular weight (Average) 2236.48

Molecular weight (Monoisotopic) 2235.12

Common amino acids DLS

Net charge -1

Instability index (II) 94.38

Aliphatic index 83.00

Grand average of hydropathicity (GRAVY) -0.880

Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID CN113549143A

Patent Title Anti-tumor polypeptide Bax-BH3, fluorescent polymer nano-micelle as well as preparation method and application of fluorescent polymer nano-micelle

Other Iinformation Not available

Other Published ID Not available