This work is licensed under a Creative Commons Attribution 4.0 International License.
SEQ ID NO.1 of Patent CN113912739A
General Information
DCTPep ID DCTPep06016
Peptide Name SEQ ID NO.1 of Patent CN113912739A
Sequence QRDMHSHRDFQPVLVALNSPLSGGMRDRG
Sequence Length 29
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
ACP Cancer targeted peptides α6β1 inhibitor
Activity Information
| Cell Line | Disease | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|
| PC-3 | Prostate carcinoma | 10% Survival=200 μg/ml | MTT assay | 24h | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target α6β1
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C137H222N48O42S2
Absent amino acids CEIKTWY
Theoretical pI 9.46
Acidic residues 3
Basic residues 6
Polar residues 7
Molecular weight (Average) 3277.69
Molecular weight (Monoisotopic) 3275.62
Common amino acids R
Net charge 3
Instability index (II) 51.37
Aliphatic index 63.79
Grand average of hydropathicity (GRAVY) -0.828
Half Life
0.8 hours (mammalian reticulocytes, in vitro).
10 min (yeast, in vivo).
10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN113912739A
Patent Title Endostatin 33 peptide with anti-tumor activity and application thereof
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.