Peptide Libraray

Tempor in-1CEa-Sp4

General Information

DCTPep ID DCTPep06023

Peptide Name Tempor in-1CEa-Sp4

Sequence FVDLKKIⓍNIIⓍSIFGK

Sequence Length 17

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

ACP Tumor active peptide Cancer targeted peptides Stapled Peptides

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
HCT 116	Colon carcinoma	IC50=25.91μM	CCK-8 assay	96h	Patent

Hemolytic Activity Low hemolysis

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Cyclic (Stapled)

Disulfide/Other Bond Stapled: Ⓧ(8) and Ⓧ (12) are cross-linked by hydrocarbon stapling

N-terminal Modification Acetylation

C-terminal Modification Amidation

Other Modification Ⓧ=(2R)-2-amino-2-methyl-6-heptenoic acid

Chiral L

Physicochemical Information

Formula Not Applicable

Absent amino acids Not Applicable

Theoretical pI Not Applicable

Acidic residues Not Applicable

Basic residues Not Applicable

Polar residues Not Applicable

Molecular weight (Average) Not Applicable

Molecular weight (Monoisotopic) Not Applicable

Common amino acids Not Applicable

Net charge Not Applicable

Instability index (II) Not Applicable

Aliphatic index Not Applicable

Grand average of hydropathicity (GRAVY) Not Applicable

Half Life
Not Applicable

Extinction coefficients
Not Applicable

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID CN114605498A

Patent Title Stapled peptide antineoplastic active compound, pharmaceutical composition and application of stapled peptide antineoplastic active compound

Other Iinformation Not available

Other Published ID Not available