Peptide Libraray

coloy(Trp-Thr-Val-Leu-Leu)

General Information

DCTPep ID DCTPep06044

Peptide Name coloy(Trp-Thr-Val-Leu-Leu)

Sequence WTVLL

Sequence Length 5

UniProt ID Not available

PubChem CID Not available

Origin Frog fecal mildew

Type Native peptide

Classification

ACP Tumor active peptide Cancer targeted peptides α-Glucosidase inhibitor

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
HepG2	Hepatoblastoma	IC50=51.50μg/ml	CCK-8 assay	Not available	Patent

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target α-Glucosidase

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Cyclic

Disulfide/Other Bond NCB: Trp1<--->Leu5

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula Not Applicable

Absent amino acids Not Applicable

Theoretical pI Not Applicable

Acidic residues Not Applicable

Basic residues Not Applicable

Polar residues Not Applicable

Molecular weight (Average) Not Applicable

Molecular weight (Monoisotopic) Not Applicable

Common amino acids Not Applicable

Net charge Not Applicable

Instability index (II) Not Applicable

Aliphatic index Not Applicable

Grand average of hydropathicity (GRAVY) Not Applicable

Half Life
Not Applicable

Extinction coefficients
Not Applicable

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID CN115636870A

Patent Title Cyclochrome-threo-valine-leucine-leucine peptide with hepatoma carcinoma cytotoxicity and alpha-glucosidase inhibitory activity and preparation method of cyclo-threo-valine-leucine peptide

Other Iinformation Not available

Other Published ID Not available