LT-1

General Information


DCTPep ID  DCTPep06076

Peptide Name   LT-1

Sequence  ASAIYSVETINDGNFHIVELLA

Sequence Length  22

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic (Derived from SLIT2 protein)

Type  Synthetic peptide

Classification

  

ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C107H166N26O35

Absent amino acids  CKMPQRW

Theoretical pI  4.13

Acidic residues  3

Basic residues  1

Polar residues  7

Molecular weight (Average)  2376.65

Molecular weight (Monoisotopic)  2375.2

Common amino acids  AI

Net charge  -2

Instability index (II)  14.97

Aliphatic index  128.64

Grand average of hydropathicity (GRAVY)  0.591

Half Life 
  4.4 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 0.627

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID CN111032679A

Patent Title  Peptides for Cancer Treatment

Other Iinformation  Not available

Other Published ID  Not available




DCTPep is developed by Dr.Zheng's team.