This work is licensed under a Creative Commons Attribution 4.0 International License.
General Information
DCTPep ID DCTPep06140
Peptide Name
Sequence CRGDHAGDC
Sequence Length 9
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
ACP Cancer targeted peptides Tumor-homing peptides Arsenic- containing anti-cancer agent
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Bridging: Cys1<---As--->Cys9
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C33H52N14O14S2
Absent amino acids EFIKLMNPQSTVWY
Theoretical pI 5.21
Acidic residues 2
Basic residues 2
Polar residues 4
Molecular weight (Average) 932.98
Molecular weight (Monoisotopic) 932.32
Common amino acids CDG
Net charge 0
Instability index (II) -0.54
Aliphatic index 11.11
Grand average of hydropathicity (GRAVY) -0.967
Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.134, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN111344298A
Patent Title Anti-cancer agent
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.