General Information


DCTPep ID  DCTPep06148

Peptide Name  

Sequence  CYDSWHYWC

Sequence Length  9

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

ACP Cancer targeted peptides Tumor-homing peptides Arsenic- containing anti-cancer agent



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  Bridging: Cys1<---As--->Cys9

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C59H67N13O15S2

Absent amino acids  AEFGIKLMNPQRTV

Theoretical pI  5.08

Acidic residues  1

Basic residues  1

Polar residues  5

Molecular weight (Average)  1262.38

Molecular weight (Monoisotopic)  1261.43

Common amino acids  CWY

Net charge  0

Instability index (II)  120.21

Aliphatic index  0.00

Grand average of hydropathicity (GRAVY)  -0.767

Half Life 
  1.2 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 14105
  Abs 0.1% (=1 g/l) 11.173, assuming all pairs of Cys residues form cystines
  Ext. coefficient 13980
  Abs 0.1% (=1 g/l) 11.074, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID CN111344298A

Patent Title  Anti-cancer agent

Other Iinformation  Not available

Other Published ID  Not available




DCTPep is developed by Dr.Zheng's team.